NOCTIS
Advanced Cellular Renewing Serum
A skincare treatment built around the electron. At its center is Phyredox®, a proprietary complex formulated to support mitochondrial function and sustain antioxidant activity continuously — where conventional antioxidants exhaust after a single reaction, this one keeps cycling.
Included is over 20 peer-reviewed actives and rare botanical humectants, each chosen for a specific role, including to defend against inflammation, the enzymatic breakdown of collagen and elastin, and the oxidative stress that accumulates over time.
The result is skin that smooths, lines that soften, and a resilience that builds with use.
Energy to renew. Defense to protect. A formula built for both.
30-Day Satisfaction Guarantee
SUITABLE FOR
Skin that no longer renews itself as it once did, skin with signs of fatigue, stress, aging, or loss of vitality. For those seeking improved resilience and long-term skin health.
HOW TO USE
• After cleansing and toning, apply a measured dose to the face, neck, and décolleté nightly.
• Follow with a thicker serum, cream, or more occlusive step of your choice.
Choose options
Built Against Every Layer of Skin Decline
Skin shows what it's been through. Time, stress, the slow depletion of what once renewed easily. NOCTIS was built to work at each of those levels, from the cellular outward. Tap any marker to go deeper.
Power the Dermal Battery
Most formulas work on the surface of aging. But cellular energy is the prerequisite for everything else. Without it, actives stall, repair slows, and skin ages faster than it should.
CoQ10 and Methylene Blue cycle electrons at the mitochondrial level, working not just as antioxidants, but as the engine behind the engine. We include both in NOCTIS for exactly this reason.
Defend Before You Build
Collagen doesn't only need to be built. It needs to be protected from the enzymes actively breaking it down.
Dragon's Blood, Blue Lotus, Gotu Kola, Camellia Sinensis, and Vitis Vinifera are each independently studied for their inhibition of collagenase or elastase (enzymes that break collagen and elastin down). Together, they form a rare convergence. Stop the loss first.
Stop the Signal
Every expression line begins as a signal. Acetyl Octapeptide-3 interrupts it — competing at the neuromuscular junction to reduce the repetitive movements and expressions that etch lines deeper over time. All without a needle.
Silence Inflammaging
At low-grade, chronic levels, inflammation silently accelerates every visible marker of aging. It is a mechanism so well-documented in longevity science it has its own name: inflammaging.
Gotu Kola, Spirulina, and Apigenin-rich Dual Chamomile are in NOCTIS specifically to interrupt it at the source.
LONGEVITY RUNS ON REDOX
PHYREDOX® keeps the antioxidant loop going.
Where most formulas neutralize damage after it forms, Phyredox® targets oxidative stress at the source. A formula that doesn't deplete. It cycles.
Key Actives
A proprietary cycling antioxidant complex that sustains and amplifies everything around it. Where conventional antioxidants deplete on contact, Phyredox® regenerates - keeping the full formula working longer and deeper.
Centella triterpenes have been studied to increase collagen synthesis and intracellular fibronectin content, improving the tensile strength of skin.* Calms inflammation, soothes, and visibly reduces redness.** An ancient botanical with extraordinary modern evidence.
A rare phyto-resin rich in polyphenols, studied to support barrier function and overall skin integrity.*
Vital to every cell's energy cycle. CoQ10 boosts skin firmness, resilience, and youthful appearance. Not just an antioxidant, but a powerful energy cycler. Peer-reviewed studies show it can penetrate the epidermis and visibly reduce wrinkle depth.** We feature phospholipid-encapsulated CoQ10 to protect and deliver it with enhanced precision.
Worn to bed - thirty nights.
Applied once nightly during skin's natural renewal cycle. With continued use, fine lines appear softer, texture smoother, complexion more even.
*Shown at baseline (left) and after 30 days of once-daily, NOCTIS only use.
Science this considered is rare.
Over twenty peer-reviewed actives, each chosen for a specific role — and each connected within a single cycling network.
100% would recommend
Here's what they're saying. From first application - and beyond.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7730717/
https://www.mdpi.com/2079-9284/12/3/87
https://pmc.ncbi.nlm.nih.gov/articles/PMC10295438/
https://pmc.ncbi.nlm.nih.gov/articles/PMC10295438/
https://pubmed.ncbi.nlm.nih.gov/19469932/
https://pmc.ncbi.nlm.nih.gov/articles/PMC8459234/
https://pmc.ncbi.nlm.nih.gov/articles/PMC8459234/
https://www.spandidos-publications.com/10.3892/ijmm.2016.2600
https://www.sciencedirect.com/science/article/abs/pii/S001448352030378X
https://journals.plos.org/plosone/article
https://pubmed.ncbi.nlm.nih.gov/12168090/
https://pubmed.ncbi.nlm.nih.gov/40340419/