NOCTIS Advanced Cellular Renewing Serum
PROTECT • RENEW • CYCLE
An advanced overnight serum that helps skin look smoother, softer, and more resilient with continued use.
A silken, water-light texture that absorbs to nothing. Powered by pro-longevity PHYREDOX™, botanical concentrates, and a targeted neuropeptide to support skin renewal while you sleep. For skin that looks better the longer you use it.
ABOUT
An advanced overnight treatment for healthier skin, longer. While you sleep, NOCTIS supports the skin's renewal pathways — so skin wakes replenished, calm, and looks smoother and more resilient the longer you use it.
A targeted peptide and over 20 clinically studied actives come together, including rare botanical concentrates: wild grape, Egyptian blue lotus, gotu kola, dragon’s blood. Each studied for a documented role in defending the collagen and elastin matrix, before further loss becomes visible.
At its heart is Phyredox™, our proprietary electron-cycling complex, keeping antioxidant activity in motion. Around it, plant-derived lipid vesicles — inspired by exosome science — carry that activity into skin's upper layers, for absorption that's more even, and skin that looks smoother and more alive.
KEY BENEFITS
— Phyredox™ supports cellular energy, redox balance, and mito-function
— A botanical network — green tea, centella, blue lotus — studied for helping defend collagen and elastin against the enzymes that break them down over time.
— A dual-chamomile complex and allantoin help soothe the low-grade stress that wears on skin long before it shows.
— Glycosphingolipids and Sodium PCA dissolve into the barrier through the night, tending the lipid matrix and replenishing what skin draws on to feel supple and resilient.
SUITABLE FOR
Skin that no longer renews as it once did — skin that reads tired, stressed, or worn by time. For those seeking resilience, and health that holds over time.
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LONGEVITY RUNS ON REDOX
The Night Has a Current
At the center, PHYREDOX™ is built around electron-shuttling chemistry: a tiny relay at the heart of a night treatment with more going on beneath the surface.
Key Actives
PHYREDOX™ brings together two redox-active molecules with distinct roles in electron transfer. Alongside botanical polyphenols, it gives NOCTIS a more layered approach to antioxidant care, made for the long night ahead.
Centella contains triterpenes that have been studied to increase collagen synthesis and intracellular fibronectin content, improving the tensile strength of skin.* Calms inflammation, soothes, and visibly reduces redness.** An ancient botanical with extraordinary modern evidence.
A rare Amazonian phyto-resin, traditionally used as a liquid bandage, that delivers proanthocyanidins and polyphenols to help support barrier function, calm irritation, and maintain skin integrity.*
Vital to every cell's energy cycle. CoQ10 is a native carrier in the mitochondrial electron transport chain — part of how cells make energy. It boosts skin firmness, resilience, and youthful appearance. Not just an antioxidant, but a powerful energy cycler. Peer-reviewed studies show it can penetrate the epidermis and visibly reduce wrinkle depth.** We feature phospholipid-encapsulated CoQ10 to protect and deliver it with enhanced precision.
Night Care Built Around the Electron
A lightweight, fast-absorbing overnight serum built around electron-cycling molecules, botanical extracts, and a targeted peptide, delivered via exosome-inspired plant lipid vesicles for more even absorption and support of the skin’s overnight renewal.
Visibly softens fine lines, evens skin tone, and enhances skin resilience & health over time. Use nightly for best results.
A Treatment With Range
NOCTIS brings together four complementary elements to support the look of skin through the cumulative demands of daily life. Each layer targets a distinct mechanism of skin aging & decline - working in sequence. Select a marker to explore.
Power the Dermal Battery
Skin runs on energy, and makes less of it with time. At the redox heart of the formula, CoQ10 and methylene blue support the current that renewal runs on — the energy skin draws on to look renewed, rested, and alive.
Defend Before You Build
Collagen doesn't only need to be built. It needs to be defended from the enzymes working against it.
Dragon's Blood, Blue Lotus, Gotu Kola, Camellia Sinensis, and Vitis Vinifera are each independently studied for their ability to inhibit collagenase and elastase — the enzymes responsible for breaking down collagen and elastin over time. Together, they form a rare convergence of botanical defense.
Soften the Signal
The lines we repeat become the lines we keep. Acetyl Octapeptide-3 helps relax the look of expression — visibly softening the fine lines that repeated movement etches over time. The smoothing, without the needle.
Calm What Wears on Skin
Much of what reads as aging begins as subtle, low-grade inflammation that accumulates long before it shows. A dual-chamomile apigenin complex helps calm visible redness and stress, leaving skin looking more even, more rested, more resilient with use.
How to Use
After cleansing and toning, use as a treatment layer nightly. Apply a measured dose to the face, neck, and décolleté.
Follow with thicker serums, a cream, or more occlusive step of your choice.
Intelligent Antioxidant System
A next-gen approach to everyday skin resilience.
Neurodermal Support
Neuro-calming actives help soothe stressed or inflamed skin.
Proven Botanicals
Peer-reviewed botanicals specifically chosen for elastin & collagen support.
Science this considered is rare
Our biotech‑luxury formula delivers 6× more scientifically validated active ingredients than the average leading luxury serum. Featuring over twenty peer-reviewed actives, each chosen for a specific role involved in the aging process.
Product Questions?
FAQs
Redox is short for reduction-oxidation — the chemical exchange of electrons between molecules. It is the same fundamental process behind a cut apple browning or metal rusting; at a cellular scale, it is also part of how skin generates energy, communicates, and responds to the world around it.
Antioxidants participate in that exchange. They can donate or accept electrons, helping prevent highly reactive molecules from pulling electrons from the lipids and proteins that give skin its smoothness, comfort, and visible integrity. Some antioxidant systems can also be regenerated, extending their role beyond a single encounter.
Noctis was built around a more specific question than whether an ingredient is “an antioxidant.” We looked at skin’s redox environment as a living system: where electron exchange occurs, what becomes vulnerable when that balance shifts, and which materials can work together with real biological logic.
The result is antioxidant care rethought as formulation architecture. With redox-active molecules composed alongside skin-mimetic lipids, water-binding amino acids, and targeted bioactives. Each is there not simply to perform alone, but to make the system around it more intelligent.
PHYREDOX™ is Arbor Skin’s proprietary electron-cycling complex. It provides the formula’s redox-active center and is designed to support antioxidant activity within NOCTIS.
Our complex, paired together, is built to keep antioxidant activity in motion at the level where skin makes its energy, before damage rears more of its head.
In NOCTIS, PHYREDOX™ is one part of a powerful, broader nightly formula system. Its redox-active materials are chosen to exist within a wider, skin-affine system of phospholipids, glycosphingolipids, water-binding factors, amino acids, peptide, and targeted botanical extracts.
The intention is a formula whose elements have a real, biological reason to coexist.
No. NOCTIS does not contain human exosomes. It contains plant-derived lipid vesicles inspired by the structure of naturally occurring vesicles.
These lipids are used as part of the formula’s delivery architecture, helping distribute components more evenly across the skin’s surface layers.
Use after cleansing and any water-light treatment steps, and before moisturizer or facial oil.
A simple evening routine might look like:
- Cleanser
- NOCTIS
- Moisturizer
Skin can feel softer, more comfortable, and more hydrated quickly and upon use. Changes in the appearance of texture, fine lines, and overall resilience typically build with consistent use over several weeks.
The before-and-after imagery shown for NOCTIS reflects four weeks of use. And individual results will vary.
On The Journal
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